Vitamin C Improves Endothelium-Dependent Vasodilation in Patients With Insulin-Dependent Diabetes Mellitus
نویسندگان
چکیده
منابع مشابه
Vitamin C improves endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus.
OBJECTIVES We sought to determine whether the antioxidant vitamin C improves endothelium-dependent vasodilation of forearm resistance vessels in patients with insulin-dependent diabetes mellitus. BACKGROUND Endothelium-dependent vasodilation is impaired in patients with diabetes mellitus. Oxidatively mediated degradation of endothelium-derived nitric oxide contributes to abnormal endothelium-...
متن کاملVitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus.
Endothelium-dependent vasodilation is impaired in humans with diabetes mellitus. Inactivation of endothelium-derived nitric oxide by oxygen-derived free radicals contributes to abnormal vascular reactivity in experimental models of diabetes. To determine whether this observation is relevant to humans, we tested the hypothesis that the antioxidant, vitamin C, could improve endothelium-dependent ...
متن کاملImpaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus.
BACKGROUND Endothelium-dependent vasodilation is abnormal in experimental models of diabetes mellitus. We postulated that abnormalities of endothelial function are also present in patients with insulin-dependent diabetes mellitus and may contribute to the pathogenesis of vascular disease in these individuals. METHODS AND RESULTS Vascular reactivity was measured in the forearm resistance vesse...
متن کاملInsulin effect on Leptin Concentration in Children with New Onset Insulin Dependent Diabetes Mellitus
Objective: Serum Leptin concentration reflects the body fat mass. There is controversial reports about the insulin effect on serum Leptin concentration. We wanted to examine the effect of insulin therapy on serum Leptin in children with new onset type I diabetes. Materials and Methods: This was a Cross-Sectional study in Children's Medical Center on 34 children who had new onset type I diabe...
متن کاملVitamin E administration improves impairment of endothelium-dependent vasodilation in patients with coronary spastic angina.
OBJECTIVES We examined the effects of oral administration of vitamin E, an antioxidant, on endothelium-dependent vasodilation in patients with coronary spastic angina. BACKGROUND We have recently reported that endothelium-dependent vasodilation is impaired in patients with coronary spastic angina (CSA). Furthermore, it is known that oxidative stress may play an important role in the impairmen...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1998
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(97)00536-6